Pyometra in dogs is a silent but urgent medical emergency. For owners of unspayed female dogs, it poses a serious health risk. This condition is a severe infection of the uterus. It can quickly go from mild signs to a life-threatening crisis in just a few days. The main treatment is usually surgery. This procedure is life-saving but can be emotionally challenging for pet owners. Knowing what the surgery involves, why it’s needed, and how to manage recovery is vital for making informed choices during stressful times.
What You’ll Learn in This Guide
This guide covers all aspects of pyometra and its surgery. We’ll explain the medical terms, outline the surgery steps, and give clear instructions for recovery. You’ll learn what pyometra is, how to spot its signs, what happens during diagnosis and treatment, and how to care for your dog afterwards.
Why Pyometra is an Emergency for Dogs
Pyometra is not an infection to ignore or treat with home antibiotics. The uterus turns into a sealed sac filled with bacteria and pus. This releases toxins into the bloodstream, which can lead to sepsis. Sepsis causes a severe inflammatory response, resulting in organ failure, septic shock, and death. Time is crucial. The longer the infection lasts, the greater the risk of uterine rupture. This can spill pus into the abdomen and is often fatal. Immediate veterinary care is vital to save the dog’s life. Sadly, pyometra affects many intact female (non-spayed) dogs. Some data shows it impacts up to 25% of non-spayed female dogs by age 10.
What is Pyometra? Understanding the Condition
Definition: Infection of the Uterus in Dogs
At its core, pyometra is a severe bacterial infection and subsequent accumulation of pus within the uterus. The name itself is derived from Latin: pyo (pus) and metra (uterus). It transforms the uterus from a healthy reproductive organ into a diseased, fragile, and toxic-filled sac. This condition almost exclusively affects intact (unspayed) female dogs.

The Role of Hormones: How the Reproductive Cycle Leads to Pyometra
Pyometra is fundamentally a hormonally driven disease. Each time a dog goes through her heat cycle (estrus), her body prepares for a potential pregnancy. After the heat, progesterone levels stay high for weeks. This thickens the uterine lining and reduces contractions. This creates an ideal, nutrient-rich environment for bacteria to thrive. Repeated hormonal changes over time can cause uterine tissue changes, making it more prone to infection.
The Link to Cystic Endometrial Hyperplasia (CEH) and Endometritis
Repeated exposure to progesterone can lead to Cystic Endometrial Hyperplasia (CEH). This condition causes the uterine lining to develop cysts and thicken abnormally. This thickened, cystic tissue is a perfect breeding ground for bacteria. Endometritis, an inflammation of the uterine lining, often precedes or occurs alongside pyometra. CEH makes it harder for the uterus to remove bacteria from the vagina. This can lead to a serious pyometra infection.
The Bacterial Culprits: Understanding the Infection (e.g., E. coli)
The bacteria that lead to pyometra usually live in the dog’s vaginal canal. The most common culprit is Escherichia coli (E. coli). Under normal circumstances, these bacteria are harmless. When the hormonal environment in the uterus changes, the cervix relaxes during the heat cycle. This lets the bacteria move up into the uterus. Once inside the progesterone-primed environment, they multiply rapidly, leading to a massive infection.
Recognising the Signs: When to Seek Emergency Veterinary Care
Common Clinical Signs of Pyometra (Open vs. Closed Cervix)
The symptoms of pyometra can differ a lot. This depends on one key factor: whether the cervix is open or closed.
- Open-Cervix Pyometra: If the cervix remains open, the pus can drain from the uterus to the outside. Owners might see a smelly vaginal discharge that could be bloody, yellow, or green. Dogs with open pyometra might appear less sick at first. This is because the toxins aren’t fully trapped inside.
- Closed-Cervix Pyometra: This is the more dangerous form. The cervix is closed, trapping all the pus and bacteria inside the uterus. The uterus swells dramatically, like a large abscess. Dogs with a closed cervix can get sick fast. They show more severe signs because toxins enter the bloodstream quickly. There is no vaginal discharge.

Subtle vs. Severe Symptoms: What to Watch For in Your Dog’s General Activity
Whether open or closed, several general signs of illness are common. Watch for:
- Lethargy and depression
- Loss of appetite
- Increased thirst and urination (polydipsia/polyuria)
- Vomiting or diarrhoea
- A swollen or distended abdomen
- Fever
- Pale gums
A dog might show small signs, like acting a bit “off” or drinking more water. But this can quickly lead to serious illness.
Why Early Detection is Crucial: The Risk of Sepsis and Rapid Deterioration
Early detection is paramount because of the risk of sepsis. Bacteria multiply and release strong toxins. These toxins enter the bloodstream and trigger a body-wide inflammatory response. This affects vital organs, particularly the kidneys and heart. The patient can quickly go into septic shock, a state of cardiovascular collapse. Without immediate and aggressive treatment, the condition is fatal.
Diagnosing Pyometra: The Veterinary Approach
The Initial Physical Examination and Patient History
When you arrive at the Petyaari Pet Clinic, our veterinarian will start by taking a detailed patient history. They will ask about your dog’s last heat cycle. They’ll want to know if you noticed symptoms like discharge or increased thirst. They’ll also check on her overall health. During the exam, the veterinarian may do several things. They might feel for an enlarged uterus in the abdomen. They’ll check for fever and assess gum colour for signs of shock. Also, they will look for vaginal discharge.
Diagnostic Imaging: X-rays and Ultrasound Examination
Imaging is key to confirming the diagnosis.
- X-rays (Radiographs): An abdominal X-ray can show a large, fluid-filled tube. This is the pus-filled uterus. This is especially clear in cases of closed-cervix pyometra.
- Ultrasound: An ultrasound is the most definitive diagnostic tool. It lets the veterinarian see the uterine walls and the fluid. This helps confirm whether it is pus or a pregnancy. Ultrasound can detect pyometra earlier and more accurately than X-rays.
Blood Work: Assessing White Blood Cell Count, Globulins, and Other Markers
Blood tests give important details about a patient’s overall health and how serious the infection is. A complete blood count (CBC) usually shows a high white blood cell count. This indicates a significant infection. Blood chemistry panels check how well organs work, especially the kidneys. Bacterial toxins can harm these organs. Elevated globulins (a type of protein) also point toward significant inflammation and infection.
Differentiating from Other Conditions
The vet needs to check for other issues that have similar symptoms. These include pregnancy, a uterine tumour, or a urinary tract infection. The combination of patient history (an unspayed female), clinical signs, blood work, and definitive imaging allows for an accurate diagnosis.
Understanding Treatment Options
Surgical Management: The Gold Standard for Pyometra
The universally recommended and most effective treatment for pyometra is emergency surgery. Delaying the procedure significantly increases the risk of fatal complications. The cost of this life-saving surgery can be high, averaging between Rs 12,000 and Rs 30,000. In complex emergency cases, it may go even higher.
Why Ovariohysterectomy (OVH) is the Recommended Treatment
An ovariohysterectomy (OVH), or spay, is the surgical procedure performed. It involves the complete removal of both the infected uterus and the ovaries. This is the treatment of choice for three key reasons:
- It is curative: Taking out the source of the infection (the uterus) and the hormonal drivers (the ovaries) completely fixes the issue.
- It’s Immediate: The procedure quickly stops toxins from being absorbed into the bloodstream.
- It’s Permanent: It stops pyometra from coming back and removes the chance of future uterine or ovarian diseases. Also, spaying offers long-term health benefits. Spayed dogs, on average, live 23% longer than those that are not spayed.
Medical Management: When is it an Option, and What are the Limitations?
Medical management, which uses hormones and antibiotics to try to empty the uterus, is rarely recommended. It is usually only for young, valuable breeding dogs with open-cervix pyometra when the owner wants to keep their fertility. The limitations and risks are significant:
- High Risk of Failure: It may not work well, and the dog could get very sick during treatment.
- High Recurrence Rate: The uterine condition (CEH) stays, so pyometra is likely to return in the next heat cycle.
- Side Effects: The medications can cause serious side effects like uterine rupture.
Exploring Medications like Prostaglandins, Aglepristone, Cloprostenol, and Cabergoline
Medical protocols involve a combination of drugs. Prostaglandins (like cloprostenol) are used to stimulate uterine contractions to expel the pus. Aglepristone (not available in all countries) blocks progesterone receptors. This helps open the cervix and empty the uterus. Cabergoline may be used to reduce prolactin levels. These treatments need intensive hospitalisation and monitoring.
Pyometra Surgery: A Step-by-Step Guide for Owners
Pre-Surgical Preparation: Ensuring Your Dog’s Safety
A dog with pyometra is a high-risk surgical patient. The primary goal before anaesthesia is stabilisation. This is not a routine spay; it is a critical emergency procedure.
Pre-Anaesthetic Blood Work and IV Fluid Support
Upon diagnosis, our veterinary team will immediately place an intravenous (IV) catheter. This lets us give IV fluids. They help fix dehydration, boost blood pressure, and support organ function. Broad-spectrum IV antibiotics are also started immediately to begin fighting the systemic infection. Pre-anaesthetic blood tests confirm the diagnosis. They also help our vets to create the safest anaesthesia plan for the patient.
Anaesthesia Protocols and Monitoring
Anaesthetising a sick, potentially septic patient requires skill and constant monitoring. A dedicated veterinarian will monitor the dog’s heart rate, blood pressure, oxygen levels, and temperature throughout the entire procedure. The anaesthesia protocol is selected to ensure maximum stability and support for the at-risk patient.
Owner Consent and Understanding the Risks
Before surgery, our veterinarian team will discuss the procedure, the prognosis, and the potential risks with you. These risks include complications from anaesthesia, bleeding, and potential contamination of the abdomen if the fragile uterus tears. You will need to sign a consent form acknowledging that you understand these risks. The procedure has risks, but not doing the surgery is usually a fatal choice.
The Surgical Procedure: What Happens in the Operating Room
Once the patient is stabilised and anaesthetised, the pyometra surgery begins. The surgeon cuts along the dog’s abdomen. This is like a regular spay, but usually longer. It helps remove the enlarged, heavy uterus.
The Ovariohysterectomy (OVH) Procedure for Canine Pyometra
The surgeon must handle the infected uterus with extreme care. It can be quite fragile and may tear easily. This could release a large number of bacteria into the abdomen, leading to a condition called peritonitis. The surgeon isolates the uterus and ligates the blood vessels to the ovaries and uterus. Then, both organs are removed completely. After removal, the abdomen is often lavaged (flushed) with sterile fluid to remove any potential contaminants. The incision is then closed in multiple layers. Even with the seriousness of the condition, the death rate after surgery is quite low. It usually ranges from 1% to 3% in uncomplicated cases. This shows how effective the procedure is when done quickly.

Post-Operative Recovery: The Path to Healing
Immediate Hospitalisation and Monitoring
After pyometra surgery, your dog will stay in the hospital for at least 24 to 48 hours, and sometimes longer, depending on the pet’s condition. During this crucial time, she will keep getting IV fluids, antibiotics, and strong pain meds. The veterinary team will check her temperature, mood, and appetite. They will also look at the surgical incision for swelling or discharge. This close monitoring is crucial to make sure she is recovering from the anaesthesia and the infection’s effects. If the pet’s condition is stable, daily hospital visits are recommended for 1-2 days.
Bringing Your Dog Home: The First Two Weeks
Once your veterinarian determines she is stable, your dog can continue her recovery at home. This period requires careful management.
- Medication: You will be sent home with oral antibiotics and pain relievers. It’s important to give all medications as prescribed. Finish the full course of antibiotics, even if your dog looks better.
- Incision Care: Check the surgical incision daily for redness, swelling, or discharge. Do not allow your dog to lick or chew at the site. An Elizabethan collar (e-collar or “cone”) is mandatory to prevent her from damaging the sutures.
- Activity Restriction: For the first 10-14 days, activity must be strictly limited. This means no running, jumping, or rough play. Leash walks should be short and for bathroom purposes only.
- Feeding: Your dog may have a reduced appetite for a day or two. Offer small, frequent meals of a bland, easily digestible diet as recommended by your veterinarian.
Long-Term Prognosis and What to Expect
The prognosis for dogs who undergo timely pyometra surgery is excellent. Once the infected uterus and ovaries are removed, the source of the problem is gone for good. Most dogs make a full recovery and return to their normal, happy selves within a few weeks. They won’t face long-term health issues from the surgery. Plus, they’re safe from future reproductive diseases.
Conclusion
Pyometra is a serious and dangerous condition. However, it is treatable and, most importantly, preventable. For owners of unspayed female dogs, spotting signs of illness is crucial. Look for signs like lethargy, increased thirst, or vaginal discharge. These clues are your first line of defence. When pyometra is diagnosed, prompt emergency ovariohysterectomy is not just the best option; it is the only option for saving your dog’s life. The diagnosis and surgery can be scary, but the procedure is very successful. The key point for dog owners is that the best way to handle pyometra is to prevent it completely. Spaying your dog early removes the risk. This way, she won’t have to deal with this serious infection. If you’re worried about your unspayed dog’s health, call your vet right away. It might save her life.